School of Biological Sciences
Buchanan Chair of Genetics
More details on Research ExplorerA screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay
(10 pages) 8 Mar 2023 in Scientific Reports, vol. 13
DOI: https://doi.org/10.1038/s41598-023-29915-z
Research output: Contribution to Journal › Article (Published)
Structure of SALL4 zinc-finger domain reveals link between AT-rich DNA binding and Okihiro syndrome
(13 pages) 12 Jan 2023 in Life Science Alliance, vol. 6
DOI: https://doi.org/10.26508/lsa.202201588
Research output: Contribution to Journal › Article (Published)
A critique of the hypothesis that CA repeats are primary targets of neuronal MeCP2
(9 pages) 1 Dec 2022 in Life Science Alliance, vol. 5
DOI: https://doi.org/10.26508/lsa.202201522
Research output: Contribution to Journal › Article (Published)
High-throughput sequencing SELEX for the determination of DNA-binding protein specificities in vitro
(21 pages) 16 Sep 2022 in STAR Protocols, vol. 3
DOI: https://doi.org/10.1016/j.xpro.2022.101490
Research output: Contribution to Journal › Article (Published)
Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
(28 pages) 16 Sep 2022 in iScience, vol. 25
DOI: https://doi.org/10.1016/j.isci.2022.104966
Research output: Contribution to Journal › Article (Published)
Comparative analysis of potential broad-spectrum neuronal Cre drivers
(14 pages) 8 Jul 2022 in Wellcome Open Research , vol. 7
DOI: https://doi.org/10.12688/wellcomeopenres.17965.1
Research output: Contribution to Journal › Article (Published)
Genetic therapies for neurological disorders
(7 pages) 22 Nov 2021 in Human Genetics
DOI: https://doi.org/10.1007/s00439-021-02399-5
Research output: Contribution to Journal › Review article (E-pub ahead of print)
Neuronal non-CG methylation is an essential target for MeCP2 function
(16 pages) 18 Mar 2021 in Molecular Cell, vol. 81, pp. P1260-1275.E12
DOI: https://doi.org/10.1016/j.molcel.2021.01.011
Research output: Contribution to Journal › Article (Published)
SALL4 controls cell fate in response to DNA base composition
(14 pages) 18 Feb 2021 in Molecular Cell, vol. 81, pp. 845-858
DOI: https://doi.org/10.1016/j.molcel.2020.11.046
Research output: Contribution to Journal › Article (Published)
Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing
(14 pages) 13 Oct 2020 in PLoS Genetics, vol. 16
DOI: https://doi.org/10.1371/journal.pgen.1009087
Research output: Contribution to Journal › Article (Published)
DNA methylation: Mega-year inheritance with the help of Darwin
6 Apr 2020 in Current Biology, vol. 30, pp. PR319-R321
DOI: https://doi.org/10.1016/j.cub.2020.02.034
Research output: Contribution to Journal › Review article (Published)
The molecular basis of MeCP2 function in the brain
13 Mar 2020 in Journal of Molecular Biology, vol. 432
DOI: https://doi.org/10.1016/j.jmb.2019.10.004
Research output: Contribution to Journal › Article (Published)
Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo
17 Feb 2020 in Nucleic Acids Research
DOI: https://doi.org/10.1093/nar/gkaa102
Research output: Contribution to Journal › Article (Published)
The selfishness of law-abiding genes
26 Oct 2019 in Trends in Genetics
DOI: https://doi.org/10.1016/j.tig.2019.10.002
Research output: Contribution to Journal › Article (Published)
Quantitative modelling predicts the impact of DNA methylation on RNA polymerase II traffic
(6 pages) 23 Jul 2019 in Proceedings of the National Academy of Sciences (PNAS), vol. 116, pp. 14995-15000
DOI: https://doi.org/10.1073/pnas.1903549116
Research output: Contribution to Journal › Article (Published)
An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development
(14 pages) 13 Mar 2019 in Epigenomes, vol. 3
DOI: https://doi.org/10.3390/epigenomes3010007
Research output: Contribution to Journal › Article (Published)
R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes
(21 pages) 7 Mar 2019 in Molecular Cell, vol. 73, pp. 930-945
DOI: https://doi.org/10.1016/j.molcel.2018.12.016
Research output: Contribution to Journal › Article (Published)
Toxicity of overexpressed MeCP2 is independent of HDAC3 activity
(11 pages) 1 Dec 2018 in Genes and Development, vol. 32, pp. 1514-1524
DOI: https://doi.org/10.1101/gad.320325.118
Research output: Contribution to Journal › Article (Published)
Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2
(8 pages) 28 Aug 2018 in Cell Reports, vol. 24, pp. 2213-2220
DOI: https://doi.org/10.1016/j.celrep.2018.07.099
Research output: Contribution to Journal › Article (Published)
A mutation-led search for novel functional domains in MeCP2
(15 pages) 15 Jul 2018 in Human Molecular Genetics, vol. 27, pp. 2531-2545
DOI: https://doi.org/10.1093/hmg/ddy159
Research output: Contribution to Journal › Article (Published)